Role of citrate and other methods of anticoagulation in patients with severe liver failure requiring continuous renal replacement therapy
نویسندگان
چکیده
Anticoagulation is required during continuous renal replacement therapy to prevent filter clotting and optimize filter performance. However, anticoagulation may also be associated with serious bleeding complications. Patients with liver failure often suffer from underlying coagulopathy and are especially prone to anticoagulation complications. The aim of this review is to present the unique features of patients with hepatic injury in terms of anticoagulation disorders and to analyze data on safety and efficacy of the different anticoagulation methods for liver failure patients undergoing continuous renal replacement therapy.
منابع مشابه
Efficacy and safety of regional citrate anticoagulation in liver transplant patients requiring post-operative renal replacement therapy.
BACKGROUND Liver transplant patients with acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) early post-operatively are at high risk for bleeding. Using heparin for anticoagulation during CRRT may contribute to the increased bleeding risk. Regional anticoagulation with citrate may decrease the risk of bleeding. However, citrate anticoagulation may be associated with...
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عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2009